Dynamics and epigenetic signature of regulatory T-cells following antiretroviral therapy initiation in acute HIV infection

Background: HIV infection promotes the expansion of immunosuppressive regulatory T-cells (Tregs), contributing to immune dysfunction, tissue fibrosis and disease progression. Early antiretroviral treatment (ART) upon HIV infection improves CD4 count and decreases immune activation. However, Treg dyn...

Description complète

Détails bibliographiques

Auteurs principaux:	Alexis Yero, Tao Shi, Omar Farnos, Jean-Pierre Routy, Cécile Tremblay, Madeleine Durand, Christos Tsoukas, Cecilia T. Costiniuk, Mohammad-Ali Jenabian
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2021-09-01
Collection:	EBioMedicine
Sujets:	HIV antiretroviral therapy (ART) regulatory T-cells (Tregs) FoxP3 TGF-β1 CD39
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2352396421003637
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!