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CRISPR/Cas9-compatible plasmids enabling seven dominant genetic selection methods for the human fungal pathogen Cryptococcus neoformans

ABSTRACT Cryptococcus neoformans is the most common cause of human fungal meningitis and an important model system for studying fundamental eukaryotic biology. Genetic manipulation of this organism relies on three dominant drug resistance markers (nourseothricin acetyltransferase [NAT], neomycin pho...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Michael J. Boucher, Hiten D. Madhani
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2025-11-01
Schriftenreihe:Microbiology Spectrum
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Online-Zugang:https://journals.asm.org/doi/10.1128/spectrum.01935-25
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