Fludarabine attenuates inflammation and dysregulated autophagy in alveolar macrophages via inhibition of STAT1/IRF1 pathway

Abstract Background Acute lung injury (ALI), including its most severe form, acute respiratory distress syndrome (ARDS), is a common cause of acute hypoxemic respiratory failure. Although its clinical characteristics have been well characterized, the relevant mechanism remains unclear. An imbalance...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Jooyeon Lee, Jeong-Ran Park, Hanbyeol Lee, Seok-Ho Hong, Woo Jin Kim, Oliver Eickelberg, Sung-Min Park, Semin Ryu, Sung Joon Cho, Seung-Jin Kim, Se-Ran Yang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-05-01
Edice:	Laboratory Animal Research
Témata:	Acute lung injury STAT1 IRF1 Fludarabine Autophagy Inflammation
On-line přístup:	https://doi.org/10.1186/s42826-025-00245-7
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!