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Endothelial cell damage in patients with acute graft versus host disease receiving treatment with extracorporeal photopheresis

IntroductionExtracorporeal photopheresis (ECP) is a safe, effective treatment for steroid-refractory acute GVHD (SR-aGVHD). Endothelial damage is a pathological substrate of aGVHD. MethodsEndothelial damage biomarkers were measured in SR-aGVHD patients' plasma before (PRE) and 1-month after initiati...

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Principais autores: Julia Martinez-Sanchez, Paola Charry, Ana Belén Moreno-Castaño, Alex Ramos, Sergi Torramade-Moix, Helena Ventosa-Capell, Marta Palomo, Olaf Penack, María Queralt Salas, María Suárez-Lledó, Francesc Fernández-Avilés, Carmen Martínez, Laura Rosiñol, Montserrat Rovira, Enric Carreras, Miquel Lozano, Gines Escolar, Joan Cid, Maribel Diaz-Ricart
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-06-01
Serier:Frontiers in Immunology
Fag:
endothelial damage
endothelium
extracorporeal photopheresis
soluble biomarkers
steroid-refractory aGVHD
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1852600/full
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