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In Vitro Exposure to the Endocrine-Disrupting Chemical Climbazole Impairs Human Sperm Motility, Hormonal Signalling, and Mitochondrial Activity

This study explores the endocrine-disrupting effects of climbazole (CBZ), an environmental and lifestyle stressor, on male fertility. The impact of CBZ on sperm vitality, motility, and molecular pathways related to hormone receptors and apoptosis was evaluated, in non-capacitated and capacitated con...

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Principais autores: Eugenia Annunzi, Francesca Paola Luongo, Francesca Girolamo, Rosetta Ponchia, Sofia Passaponti, Paola Piomboni, Alice Luddi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-03-01
coleção:Cells
Assuntos:
endocrine-disrupting chemicals (EDCs)
male fertility
climbazole (CBZ)
semen quality
oxidative stress
Acesso em linha:https://www.mdpi.com/2073-4409/14/6/427
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