Aryl hydrocarbon receptor activation ameliorates experimental colitis by modulating the tolerogenic dendritic and regulatory T cell formation

Abstract Background Intestinal immune dysfunction is involved in the onset of Crohn’s disease (CD). Dendritic cells (DCs), antigen-presenting cells, play a key role in the maintenance of intestinal immune homeostasis. The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor wid...

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Principais autores:	Xiufang Cui, Ziping Ye, Di Wang, Yan Yang, ChunHua Jiao, Jingjing Ma, Nana Tang, Hongjie Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2022-04-01
Series:	Cell & Bioscience
Assuntos:	Aryl hydrocarbon receptor Crohn’s disease Dendritic cells Intestinal immune tolerance Treg cells
Acceso en liña:	https://doi.org/10.1186/s13578-022-00780-z
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