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Amphipathic Small Molecule AZT Compound Displays Potent Inhibitory Effects in Cancer Cell Proliferation

Cancer has been identified as a leading cause of death worldwide, and the increasing number of cancer cases threatens to shorten the average life expectancy of people. Recently, we reported a 3-azido-3-deoxythymidine (AZT)-based amphipathic small molecule, ADG-2e that revealed a notable potency agai...

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Autori principali: Pethaiah Gunasekaran, Ho Jin Han, Jung hoon Choi, Eun Kyoung Ryu, Nam Yeong Park, Geul Bang, Yeo Kyung La, Sunghyun Park, Kyubin Hwang, Hak Nam Kim, Mi-Hyun Kim, Young Ho Jeon, Nak-Kyun Soung, Jeong Kyu Bang
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-12-01
Serie:Pharmaceutics
Soggetti:
anticancer
oncosis
necrosis
drug discovery
small molecule
Accesso online:https://www.mdpi.com/1999-4923/13/12/2071
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