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Melatonin ameliorates diabetic hyperglycaemia-induced impairment of Leydig cell steroidogenic function through activation of SIRT1 pathway

Abstract Background Diabetes mellitus (DM)-related complications are important health problems worldwide. The underlying mechanisms for diabetic male subfertility/infertility are considerably complicated and need to be unveiled for therapeutic intervention. Melatonin treatment was investigated to as...

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Главные авторы: Ping Wang, Shoubing Zhang, Shuai Lin, Zhengmei Lv
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2022-08-01
Серии:Reproductive Biology and Endocrinology
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Online-ссылка:https://doi.org/10.1186/s12958-022-00991-6
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