Programmed cell death in gouty nephropathy: molecular mechanisms and therapeutic implications

Gouty nephropathy (GN) is a chronic kidney disorder driven by persistent hyperuricemia; however, its pathogenesis remains under-investigated. Emerging evidence highlights that programmed cell death (PCD) plays a central role in GN, linking disordered urate metabolism to inflammation and renal functi...

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Autors principals:	Shengyi Zhao, Bingbing Chen, He Qian, Rong Wang, Sanjin Zeng, Heguo Yan, Jian Zhang, Zhaohu Xie, Zhaofu Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2026-05-01
Col·lecció:	Frontiers in Immunology
Matèries:	autophagy ferroptosis gouty nephropathy hyperuricemia monosodium urate crystals necroptosis
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1817722/full
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