Demethylbellidifolin, a potential aldose reductase inhibitor ameliorates diabetic nephropathy by regulating the polyol pathway

Background: Lots of plants in genus Swertia are widely used in the traditional medicine as the treatment for T2DM and its complications in Asia. However, the pharmacodynamic material basis and underlying mechanisms of these plants are still incompletely studied. Inhibition of aldose reductase to reg...

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Hlavní autoři:	Haifei Xie, Qilin Tong, Zhinan Xiang, Chenggao Zhou, Luo-Sheng Wan, Jiachun Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2022-02-01
Edice:	Phytomedicine Plus
Témata:	Swertia Diabetic nephropathy Aldose reductase Db/db mice Polyol pathway
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2667031321001342
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