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Progesterone Induced Blocking Factor Reduces Hypertension and Placental Mitochondrial Dysfunction in Response to sFlt-1 during Pregnancy

Preeclampsia (PE) is characterized by new onset hypertension in association with placental ischemia, reduced fetal weight, elevated soluble fms-like tyrosine kinase-1 (sFlt-1), and placental mitochondrial (mt) dysfunction and oxidative stress (ROS). Progesterone induced blocking factor (PIBF) is a p...

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Principais autores: Evangeline Deer, Jalisa Jones, Denise C. Cornelius, Kyleigh Comley, Owen Herrock, Nathan Campbell, Sarah Fitzgerald, Tarek Ibrahim, Babbette LaMarca, Lorena M. Amaral
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-10-01
Serier:Cells
Fag:
hypertension
preeclampsia
sFlt-1
oxidative stress
placental ischemia
Online adgang:https://www.mdpi.com/2073-4409/10/11/2817
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