Polycystin-2 Mediated Calcium Signalling in the <i>Dictyostelium</i> Model for Autosomal Dominant Polycystic Kidney Disease

Autosomal dominant polycystic kidney disease (ADPKD) occurs when the proteins Polycystin-1 (PC1, <i>PKD1</i>) and Polycystin-2 (PC2, <i>PKD2</i>) contain mutations. PC1 is a large membrane receptor that can interact and form a complex with the calcium-permeable cation channel PC2. This complex local...

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Bibliografische Detailangaben

Hauptverfasser:	Claire Y. Allan, Oana Sanislav, Paul R. Fisher
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-03-01
Schriftenreihe:	Cells
Schlagworte:	ADPKD Polycystin-2 <i>Dictyostelium</i> calcium calcium signalling autophagy
Online-Zugang:	https://www.mdpi.com/2073-4409/13/7/610
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