Search and processing of Holliday junctions within long DNA by junction-resolving enzymes
Locating a four-way junction in a high background of genomic DNA is likely to be the rate-limiting step of the resolution process. This study captures the entire reaction trajectory of a nuclease targeting and resolving a DNA junction at single-molecule level.
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2022-10-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-022-33503-6 |
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