Overexpression of the human heat shock protein B1 alters obesity-related metabolic changes in a sex-dependent manner in a mouse model of metabolic syndrome

Abstract Background Obesity is a global health challenge that can lead to various complications, such as metabolic syndrome, diabetes mellitus, and cardiovascular diseases. Heat shock proteins are evolutionarily conserved chaperones that help maintain cellular protein homeostasis. Their expression i...

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Detalles Bibliográficos

Principais autores:	Zsófia Ruppert, Márta Sárközy, Bettina Rákóczi, Brigitta Dukay, Petra Hajdu, Gergő Szűcs, Zsolt Galla, Ákos Hunya, Ferenc Kovács, András Kriston, Péter Monostori, Péter Horváth, Gábor Cserni, László Tiszlavicz, Tamás Csont, László Vígh, Miklós Sántha, Zsolt Török, Melinda E. Tóth
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-08-01
Series:	Biology of Sex Differences
Assuntos:	Metabolic syndrome Apolipoprotein B-100 High-fat diet Heat-shock protein HSPB1 Sex-dependency
Acceso en liña:	https://doi.org/10.1186/s13293-025-00746-z
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