The role of platelet desialylation as a biomarker in primary immune thrombocytopenia: mechanisms and therapeutic perspectives

Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by the destruction of platelets. Although it was long believed that the critical role of autoantibodies in platelet destruction, primarily through the Fc-dependent platelet clearance pathway, recent findings indic...

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Bibliografiske detaljer

Principais autores:	Qianhui Zhang, Miao Huang, Elizabeth Rosalind Thomas, Lu Wang, Jia Liu, Xiang Li, Jiesi Luo, Wenjun Zou, Jianming Wu
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2024-06-01
Serier:	Frontiers in Immunology
Fag:	platelets sialic acid primary immune thrombocytopenia pathogenesis apoptosis
Online adgang:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1409461/full
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