SOX9 is a key component of RUNX2-regulated transcriptional circuitry in osteosarcoma

Abstract Background The absence of prominent, actionable genetic alternations in osteosarcomas (OS) implies that transcriptional and epigenetic mechanisms significantly contribute to the progression of this life-threatening form of cancer. Therefore, the identification of potential transcriptional e...

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Detalhes bibliográficos

Principais autores:	Young-Im Kim, Yu-Chou Tseng, Gamze Ayaz, Shasha Wang, Hualong Yan, Wendy du Bois, Howard Yang, Tao Zhen, Maxwell P. Lee, Paul Liu, Rosandra N. Kaplan, Jing Huang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-07-01
coleção:	Cell & Bioscience
Assuntos:	Epigenetics JMJD1C Osteosarcoma RUNX2 SOX9 Transcription
Acesso em linha:	https://doi.org/10.1186/s13578-023-01088-2
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