Inhibition of microRNA-29a alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice via upregulation of GAB1

Abstract Background The main features of bronchopulmonary dysplasia (BPD) are alveolar simplification, pulmonary growth arrest, and abnormal lung function. Multiple studies have highlighted microRNA-29 (miR-29) as a potential biomarker for lung diseases and cancers. Upregulation of miR-29a has been...

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Detalhes bibliográficos

Principais autores:	Yu Hu, Liang Xie, Jing Yu, Hongling Fu, Dan Zhou, Hanmin Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2019-12-01
coleção:	Molecular Medicine
Assuntos:	Bronchopulmonary dysplasia MicroRNA-29a GAB1 Apoptosis Hyperoxia MLE-12
Acesso em linha:	https://doi.org/10.1186/s10020-019-0127-9
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