Trends in the Recent Patent Literature on Cholinesterase Reactivators (2016–2019)

Acetylcholinesterase (AChE) is the key enzyme responsible for deactivating the ACh neurotransmitter. Irreversible or prolonged inhibition of AChE, therefore, elevates synaptic ACh leading to serious central and peripheral adverse effects which fall under the cholinergic syndrome spectra. To combat t...

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主要な著者:	Alexandre A. de Castro, Letícia C. Assis, Flávia V. Soares, Kamil Kuca, Daniel A. Polisel, Elaine F. F. da Cunha, Teodorico C. Ramalho
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2020-03-01
シリーズ:	Biomolecules
主題:	organophosphorus compounds acetylcholinesterase therapeutic potential reactivation process new trends in reactivators
オンライン･アクセス:	https://www.mdpi.com/2218-273X/10/3/436
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