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RbdB, a Rhomboid Protease Critical for SREBP Activation and Virulence in <italic toggle="yes">Aspergillus fumigatus</italic>

ABSTRACT SREBP transcription factors play a critical role in fungal virulence; however, the mechanisms of sterol regulatory element binding protein (SREBP) activation in pathogenic fungi remains ill-defined. Screening of the Neurospora crassa whole-genome deletion collection for genes involved in hy...

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Principais autores: Sourabh Dhingra, Caitlin H. Kowalski, Arsa Thammahong, Sarah R. Beattie, Katherine M. Bultman, Robert A. Cramer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016-04-01
coleção:mSphere
Assuntos:
Aspergillus fumigatus
antifungal agents
fungal pathogenesis
hypoxia
fungal virulence
sterol regulatory element binding protein
Acesso em linha:https://journals.asm.org/doi/10.1128/mSphere.00035-16
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