Placental exosomal miR-372-3p drives preeclampsia progression by inducing mitochondrial damage in RVLM neurons

Abstract Background Preeclampsia (PE) is a pregnancy-specific disorder rooted in placental dysfunction, characterized by new-onset hypertension with proteinuria and/or end-organ dysfunction, often linked to sympathetic overactivation. The rostral ventrolateral medulla (RVLM) serves as a crucial hub...

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Detalhes bibliográficos

Principais autores:	Shuai Zhang, Linping Wang, Bingjie Zhao, Tengteng Dai, Maolin Nie, Lei Tong, Qiangcheng Zeng, Wei Guo, Yongmei Shen, Dongshu Du
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	Cellular & Molecular Biology Letters
Assuntos:	Placental exosomes miR-372-3p MPC1 Rostral ventrolateral medulla Preeclampsia
Acesso em linha:	https://doi.org/10.1186/s11658-026-00929-5
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