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Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol

Avian reovirus (ARV) causing viral arthritis/tenosynovitis and viral enteritis in domestic fowl has significantly threatened on the poultry industry worldwide. ARV is a non-enveloped fusogenic virus that belongs to the Reoviridae family. Previous research revealed that cellular cholesterol in lipid...

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Principais autores: Yuyang Wang, Wei Zuo, Yangyang Zhang, Zongyi Bo, Chengcheng Zhang, Xiaorong Zhang, Yantao Wu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-06-01
Serier:Frontiers in Microbiology
Fag:
avian reovirus
cholesterol 25-hydroxylase
25-hydroxycholesterol
virus replication
interferon stimulated genes (ISG)
Online adgang:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1178005/full
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