Identification of a modulator of the actin cytoskeleton, mitochondria, nutrient metabolism and lifespan in yeast

Actin cables affect lifespan by supporting movement and inheritance of fitter mitochondria to daughter cells in yeast. Here the authors show that branched-chain amino acid (BCAA) levels affect actin cable stability and a role for YKL075C/AAN1 in control of BCAA metabolism and actin cable stability a...

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Detalhes bibliográficos

Principais autores:	Cierra N. Sing, Enrique J. Garcia, Thomas G. Lipkin, Thomas M. Huckaba, Catherine A. Tsang, Arielle C. Coughlin, Emily J. Yang, Istvan R. Boldogh, Ryo Higuchi-Sanabria, Liza A. Pon
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2022-05-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-022-30045-9
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