An α2-Adrenergic Agonist, Brimonidine, Beneficially Affects the TGF-β2-Treated Cellular Properties in an In Vitro Culture Model

We report herein on the effects of brimonidine (BRI), an α2-adrenergic agonist, on two-dimensional (2D) and three-dimensional (3D) cell-cultured TGF-β2-untreated and -treated human trabecular meshwork (HTM) cells. In the presence of TGF-β2 (5 ng/mL), (1) the effects of BRI on (1) the 2D HTM monolaye...

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Detalhes bibliográficos

Principais autores:	Megumi Watanabe, Tatsuya Sato, Yuri Tsugeno, Megumi Higashide, Masato Furuhashi, Araya Umetsu, Soma Suzuki, Yosuke Ida, Fumihito Hikage, Hiroshi Ohguro
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-07-01
coleção:	Bioengineering
Assuntos:	three-dimensional spheroid cell cultures human trabecular meshwork (HTM) brimonidine α2-adrenergic agonist TGF-β2
Acesso em linha:	https://www.mdpi.com/2306-5354/9/7/310
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