Manipulating the Subcellular Localization and Anticancer Effects of Benzophenothiaziniums by Minor Alterations of N-Alkylation

Cationic, water-soluble benzophenothiaziniums have been recognized as effective type I photosensitizers (PSs) against hypoxic tumor cells. However, the study of the structure–property relationship of this type of PS is still worth further exploration to achieve optimized photodynamic effects and min...

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Hauptverfasser:	Yanping Wu, Yuncong Chen, Shankun Yao, Shumeng Li, Hao Yuan, Fen Qi, Weijiang He, Zijian Guo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-02-01
Schriftenreihe:	Molecules
Schlagworte:	benzophenothiaziniums type I photosensitizers reactive oxygen species phototoxicity index lysosomal membrane permeabilization mitochondria membrane potential
Online-Zugang:	https://www.mdpi.com/1420-3049/28/4/1714
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