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Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita

Epidermolysis bullosa acquisita (EBA) is an autoimmune skin blistering disease characterized by IgG autoantibodies (aAb) against type VII collagen (COL7). The mechanisms controlling the formation of such aAbs and their effector functions in the skin tissue are incompletely understood. Here, we asses...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Balint Kovacs, Jenny Tillmann, Lisa-Christin Freund, Falk Nimmerjahn, Christian D. Sadik, Katja Bieber, Ralf J. Ludwig, Christian M. Karsten, Jörg Köhl
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-01-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
Fcγ receptor
epidermolysis bullosa acquisita
autoimmunity
neutrophils
IgG
animal model
Online-Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2019.03012/full
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