NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration
NCOA4 (Nuclear receptor coactivator 4) mediates the selective autophagic degradation of ferritin, the cellular cytosolic iron storage complex, thereby playing a critical role in intracellular and systemic iron homeostasis. Disruptions in iron homeostasis and autophagy are observed in several neurode...
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| Principais autores: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2019-03-01
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| Serier: | Frontiers in Neuroscience |
| Fag: | |
| Online adgang: | https://www.frontiersin.org/article/10.3389/fnins.2019.00238/full |
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