Pathway size matters: the influence of pathway granularity on over-representation (enrichment analysis) statistics
Abstract Background Enrichment or over-representation analysis is a common method used in bioinformatics studies of transcriptomics, metabolomics, and microbiome datasets. The key idea behind enrichment analysis is: given a set of significantly expressed genes (or metabolites), use that set to infer...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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BMC
2021-03-01
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| Colección: | BMC Genomics |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1186/s12864-021-07502-8 |
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