Puerarin esters mitigate oxygen and glucose deprivation-reoxygenation-induced injury in microglial cells

Abstract Puerarin esters (PAES) are novel isoflavone derivatives of puerarin. Network pharmacology analysis revealed that PAES with medium-long chain lengths may exert a neuroprotective effect against ischemic stroke through NF-κB signaling, TNF signaling, and apoptosis-related signaling pathways. T...

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Detalhes bibliográficos

Principais autores:	Lan Mo, Guang-lei Zhao, Xiao-feng Li, Ning He, Xing-long Xiao, Hai-xia Xu, Yi-gang Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-09-01
coleção:	Food Production, Processing and Nutrition
Assuntos:	Network pharmacology Puerarin Puerarin esters Microglia cells Oxygen–glucose deprivation/reoxygenation
Acesso em linha:	https://doi.org/10.1186/s43014-025-00314-3
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