bFGF-mediated pluripotency maintenance in human induced pluripotent stem cells is associated with NRAS-MAPK signaling

Abstract Background Human pluripotent stem cells (PSCs) open new windows for basic research and regenerative medicine due to their remarkable properties, i.e. their ability to self-renew indefinitely and being pluripotent. There are different, conflicting data related to the role of basic fibroblast...

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Detalhes bibliográficos

Principais autores:	Fereshteh Haghighi, Julia Dahlmann, Saeideh Nakhaei-Rad, Alexander Lang, Ingo Kutschka, Martin Zenker, George Kensah, Roland P. Piekorz, Mohammad Reza Ahmadian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-12-01
coleção:	Cell Communication and Signaling
Assuntos:	bFGF Differentiation Induced pluripotent stem cells MAPK RAS PI3K
Acesso em linha:	http://link.springer.com/article/10.1186/s12964-018-0307-1
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