The Design and Immunogenicity of an HIV-1 Clade C Pediatric Envelope Glycoprotein Stabilized by Multiple Platforms

Background: Elite-neutralizer-derived HIV-1 envelopes (Envs), which induce broadly neutralizing antibodies (bnAbs), can inform HIV-1 vaccine design by serving as templates for bnAb-eliciting vaccines. Since single Env-based immunizations are insufficient to induce bnAb responses, sequential regimens...

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Autors principals:	Sanjeev Kumar, Iván del Moral-Sánchez, Swarandeep Singh, Maddy L. Newby, Joel D. Allen, Tom P. L. Bijl, Yog Vaghani, Liang Jing, Rakesh Lodha, Eric A. Ortlund, Max Crispin, Anamika Patel, Rogier W. Sanders, Kalpana Luthra
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-01-01
Col·lecció:	Vaccines
Matèries:	HIV-1 neutralizing antibodies rabbit immunization
Accés en línia:	https://www.mdpi.com/2076-393X/13/2/110
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