Limited HIV-1 Subtype C <i>nef</i> 3′PPT Variation in Combination Antiretroviral Therapy Naïve and Experienced People Living with HIV in Botswana

Dolutegravir (DTG) is a potent anti-HIV drug that is used to treat HIV globally. There have been reports of mutations in the HIV-1 3′-polypurine tract (3′PPT) of the <i>nef</i> gene, contributing to DTG failure; however, there are limited ‘real-world’ data on this. In addition, there is a knowledge...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kaelo K. Seatla, Dorcas Maruapula, Wonderful T. Choga, Olorato Morerinyane, Shahin Lockman, Vladimir Novitsky, Ishmael Kasvosve, Sikhulile Moyo, Simani Gaseitsiwe
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-08-01
Schriftenreihe:	Pathogens
Schlagworte:	HIV-1 <i>nef</i> Botswana drug resistance mutations 3′-polypurine tract dolutegravir
Online-Zugang:	https://www.mdpi.com/2076-0817/10/8/1027
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