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Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemia

In chronic lymphocytic leukemia the balance between the pro-apoptotic and anti-apoptotic members of the bcl-2 family is involved in the pathogenesis, chemorefractoriness and clinical outcome. Moreover, the recently proposed anti-bcl-2 molecules, such as ABT-199, have emphasized the potential role of...

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Hoofdauteurs: Maria Ilaria Del Principe, Michele Dal Bo, Tamara Bittolo, Francesco Buccisano, Francesca Maria Rossi, Antonella Zucchetto, Davide Rossi, Riccardo Bomben, Luca Maurillo, Mariagiovanna Cefalo, Giovanna De Santis, Adriano Venditti, Gianluca Gaidano, Sergio Amadori, Paolo de Fabritiis, Valter Gattei, Giovanni Del Poeta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ferrata Storti Foundation 2016-01-01
Reeks:Haematologica
Online toegang:https://haematologica.org/article/view/7609
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