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CD11b+ lung dendritic cells at different stages of maturation induce Th17 or Th2 differentiation

Dendritic cells in the lung may be specialised to mediate specific types of immune function. Here the authors show that subpopulations of mouse CD11b+ lung DC at different stages of maturation and phenotype can promote Th17 or Th2 CD4+ T cell differentiation.

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Autori principali: Gentaro Izumi, Hideki Nakano, Keiko Nakano, Gregory S. Whitehead, Sara A. Grimm, Michael B. Fessler, Peer W. Karmaus, Donald N. Cook
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2021-08-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-021-25307-x
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