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The clinical and cost-effectiveness of paravertebral blockade versus thoracic epidural blockade in reducing chronic post-thoracotomy pain: TOPIC2 RCT synopsis

Background More than a third of patients undergoing thoracotomy suffer from debilitating chronic post-thoracotomy pain lasting months or years postoperatively. Aggressive management of acute pain during the perioperative period may mitigate this risk. Objective(s) To determine the clinical and cost-...

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Principais autores: Ben Shelley, Lee Middleton, Andreas Goebel, Stephen Grant, Louise Jackson, Mishal Javed, Marcus Jepson, Nandor Marczin, Rajnikant Mehta, Teresa Melody, Babu Naidu, Hannah Summers, Lajos Szentgyorgyi, Sarah Tearne, Ben Watkins, Matthew Wilson, Andrew Worrall, Joyce Yeung, Fang Gao Smith
Formato: Artigo
Idioma:Inglês
Publicado: NIHR Journals Library 2026-02-01
Series:Health Technology Assessment
Assuntos:
thoracic surgery
chronic pain
thoracic epidural blockade
paravertebral blockade
thoracotomy
thoracic anaesthesia
regional anaesthesia
Acceso en liña:https://doi.org/10.3310/GJFG1715
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