Topical WIN 55 212-2 Confers Long-Term Intraocular Pressure–Independent Neuroprotection in the DBA/2J Mouse Model of Glaucoma

Objective: To evaluate the neuroprotective efficacy of topical WIN 55 212-2 (WIN) in the DBA/2J mouse model of chronic glaucoma. Design: Preclinical controlled study. Subjects: Ninety 6-month-old DBA/2J mice (180 eyes) grouped in Untreated (UN), WIN 1%, or WIN 1% + rimonabant (RIM). Methods: In vivo...

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Bibliografische Detailangaben

Hauptverfasser:	Gabriele Gallo Afflitto, MD, Tsung-Han Chou, PhD, Mascha Louisa Korsch, PhD, Francesco Aiello, MD, PhD, Annagrazia Adornetto, PhD, Rossella Russo, PhD, Giacinto Bagetta, MD, Carlo Nucci, MD, PhD, Vittorio Porciatti, DSc
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2026-01-01
Schriftenreihe:	Ophthalmology Science
Schlagworte:	Electroretinography Endocannabinoids Glaucoma, Intraocular pressures WIN 55 212 2 mesylate
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2666914525002167
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