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Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice

Objective: In Huntington's disease (HD), the disease-causing huntingtin (HTT) protein is ubiquitously expressed and causes both central and peripheral pathology. In clinical HD, a higher body mass index has been associated with slower disease progression, indicating the role of metabolic changes in...

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Principais autores: Elna Dickson, Rana Soylu-Kucharz, Åsa Petersén, Maria Björkqvist
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2022-03-01
Series:Molecular Metabolism
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2212877822000084
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