The gut-brain axis in Alzheimer’s disease: early detection, microbial metabolites, mechanisms, and therapeutic opportunities

Alzheimer’s disease (AD), the leading cause of dementia worldwide, imposes a growing clinical and societal burden, yet no therapies have been proven to alter its progression despite decades of intensive research. As traditional targets have yielded limited success, attention has shifted to modifiabl...

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Detalhes bibliográficos

Principais autores:	Chenyu Liu, Zihan Zhu, Huang Lin, William S. Bush, Robert R. Jenq, Fabio Cominelli, Jagan A. Pillai, Jonathan L. Haines, Xiongwei Zhu, Rong Xu, Scott M. Williams, Feixiong Cheng, Liangliang Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-06-01
coleção:	Frontiers in Molecular Biosciences
Assuntos:	Alzheimer’s disease Alzheimer’s disease stages gut microbiome gut-brain axis influential factors microbiome-target therapy
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fmolb.2026.1735332/full
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