Genomic characterisation of recurrent Mycobacterium avium isolates from chronically infected patients reveals patterns of within-host evolution

Abstract Background Mycobacterium avium complex causes chronic and difficult-to-treat infection in vulnerable patient groups, and incidence is increasing worldwide. Whole genome sequencing has the potential to reveal new information about how M. avium persists over time in the human lung. Methods We...

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Ngā kaituhi matua:	Aaron M. Walsh, Emma Roycroft, Kate Hinchion, Sharee A. Basdeo, Frederick J. Sheedy, Fiona Crispie, Paul D. Cotter, Anne Marie McLaughlin, Joseph Keane, Margaret M. Fitzgibbon, Laura E. Gleeson
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2025-10-01
Rangatū:	Genome Medicine
Ngā marau:	Mycobacterium avium complex (MAC) Mycobacterium avium Nontuberculous mycobacteria (NTM) Pathogen genomics Whole genome sequencing Within-host evolution
Urunga tuihono:	https://doi.org/10.1186/s13073-025-01549-y
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