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A Glimpse in the Metal Ion Selectivity Rules: Zn(II), Cd(II) and Co(II) Interplay With Different Protein Coordination Spheres in Determining Variable Thermal Stability and Folding Scenarios

In this study, the binding properties to Zn(II), Co(II) and Cd(II) of the protein Ros87-C27D, Ros87 mutant with a CysAspHis2 coordination sphere, are investigated by means of UV–vis, CD and NMR spectroscopies. Dissociation constants, structural effects and the resulting mechanisms of folding are com...

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Hlavní autoři: Martina Dragone, Gaetano Caputo, Gianluca D’Abrosca, Getasew Shitaye, Ilaria Baglivo, Paolo Vincenzo Pedone, Luigi Russo, Roberto Fattorusso, Gaetano Malgieri, Carla Isernia
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2026-01-01
Edice:Bioinorganic Chemistry and Applications
On-line přístup:http://dx.doi.org/10.1155/bca/3380419
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