Design, synthesis, reactivity, and biological activity of nitroimidazole derivatives and their copper(II) coordination compounds

In the last 60 years, the broad spectrum of activity of nitroimidazole derivatives against anaerobic bacteria, parasites, and protozoa has permitted their use as the first choice of treatment for many infectious diseases. New compounds are needed to overcome the acquired resistance of bacteria and p...

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Autori principali:	Walter Fugarolas, Lorena Reyes-Carmona, Bruno Landeros-Rivera, Argelia Almaguer-Flores, Norah Barba-Behrens
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-02-01
Serie:	Frontiers in Chemical Biology
Soggetti:	4-nitroimidazole 5-nitroimidazole coordination behavior copper(II) complexes non-covalent interactions periodontal bacteria
Accesso online:	https://www.frontiersin.org/articles/10.3389/fchbi.2025.1736242/full
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