Inhaled clofazimine adminsitration increases antimycobacterial effect compared to oral administration in a hollow-fibre system

AIM: To compare the antimycobacterial effect of inhaled versus oral clofazimine administration with an azithromycin-ethambutol backbone. BACKGROUND: Mycobacterium avium complex causes non-tuberculous pulmonary disease. Clofazimine can replace rifampicine in combination with an azithromycin-ethambuto...

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Auteurs principaux:	Jelmer Raaijmakers, Rob E. Aarnoutse, Lindsey Te Brake, Ralf Stemkens, Heiman F.l. Wertheim, Wouter Hoefsloot, Jakko Van Ingen
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2024-12-01
Collection:	Journal of Global Antimicrobial Resistance
Sujets:	Antimycobacterial efficacy PK/PD Hollow-fibre system
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S221371652400362X
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