Genetic contribution to severe COVID-19 in adults under 60 years without major comorbidities in the German National Pandemic Cohort Network (NAPKON)

Abstract While genome-wide association studies (GWAS) have linked common genetic variants to COVID-19 susceptibility and severity, rare high-impact variants may also contribute to phenotypic heterogeneity. Inborn errors of type I interferon immunity (IFN-I-IEIs), including X-linked TLR7 deficiency,...

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প্রধান লেখক:	Ayda Abolhassani, T. Madhusankha Alawathurage, Axel Schmidt, Fabian Brand, Laura L. Kilarski, Heidi Altmann, Edgar Dahl, Sandra Frank, Siri Göpel, Frank Hanses, Johannes Christian Hellmuth, Christian Herr, Achim J. Kaasch, Robin Kobbe, Margarethe Justine Konik, Isabell Pink, Christoph Römmele, Jan Rupp, Christian S. Scheer, Marc A. Schneider, Christoph Stellbrink, Hans Christian Stubbe, Phil-Robin Tepasse, Andreas Teufel, István Vadász, Maria J. G. T. Vehreschild, Martin Witzenrath, Gabriele Anton, Isabel Bröhl, Susanne Herold, Thomas Illig, Steffi Jiru-Hillmann, Peter Krawitz, Lazar Mitrov, Alexandra Philipsen, Sina M. Pütz, Markus M. Noethen, Peter Nuernberg, Jens-Peter Reese, Olaf Riess, Stefan Schreiber, Joachim Schultze, Fridolin Steinbeis, J. Janne Vehreschild, Christian Wildberg, Kerstin U. Ludwig, Eva C. Schulte
বিন্যাস:	Artigo
ভাষা:	Inglês
প্রকাশিত:	BMC 2026-01-01
মালা:	Human Genomics
অনলাইন ব্যবহার করুন:	https://doi.org/10.1186/s40246-025-00904-9
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