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MIR4435-2HG: a key player in the novel lncRNA prognostic signatures causes early metastasis after tumor resection and poor prognosis for esophageal squamous cell carcinoma

Abstract Background Esophageal squamous cell carcinoma (ESCC) is a major histopathological type of esophageal cancer. Tumor metastasis is a critical factor that dramatically worsens the prognosis, leading to a decline in survival rates. Understanding the molecular mechanisms underlying metastasis an...

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Principais autores: Pengju Qi, Shuhua Huo, Wenchao Wu, Tengfei Zhang, Wenqian Yang, Jiaping Tang, Yuzhen Liu, Baosheng Zhao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-11-01
Serier:BMC Cancer
Fag:
ESCC
MIR4435-2HG
Metastasis
PI3K-Akt signaling pathway
Biomarker
Online adgang:https://doi.org/10.1186/s12885-025-15299-y
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