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Insights into the Potential Impact of Quetiapine on the Microglial Trajectory and Inflammatory Response in Organotypic Cortical Cultures Derived from Rat Offspring

Atypical antipsychotics currently constitute the first-line medication for schizophrenia, with quetiapine being one of the most commonly prescribed representatives of the group. Along with its specific affinity for multiple receptors, this compound exerts other biological characteristics, among whic...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Katarzyna Chamera, Katarzyna Curzytek, Kinga Kamińska, Ewa Trojan, Monika Leśkiewicz, Kinga Tylek, Magdalena Regulska, Agnieszka Basta-Kaim
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-05-01
Schriftenreihe:Biomedicines
Schlagworte:
quetiapine
lipopolysaccharide
organotypic cortical cultures
maternal immune activation
CD200Fc
microglia
Online-Zugang:https://www.mdpi.com/2227-9059/11/5/1405
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