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Cubebin Attenuates Methamphetamine-Induced Neurotoxicity Through CREB/BDNF/Caspase-3 Signaling: In Vivo and In Silico Study

<i>Background and Objectives:</i> Methamphetamine (METH) is a potent psychostimulant known to induce neurotoxicity and neurodegeneration, leading to cognitive impairment. This study aimed to explore cubebin’s potential neuroprotective effects against METH-induced cognitive deficits by investigating...

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Principais autores: Sattam Khulaif Alenezi, Khalid Saad Alharbi, Tariq G. Alsahli, Muhammad Afzal, Reem ALQahtani, Samiyah Alshehri, Imran Kazmi, Nadeem Sayyed
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-08-01
Serier:Medicina
Fag:
apoptosis
in silico
methamphetamine
neurotransmitters
neurotoxicity
oxidative stress
Online adgang:https://www.mdpi.com/1648-9144/61/9/1567
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