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Defining the Prion Type of Fatal Familial Insomnia

Fatal familial insomnia (FFI) belongs to the genetic human transmissible spongiform encephalopathies (TSE), such as genetic Creutzfeldt-Jakob disease (CJD) or Gerstmann-Straeussler-Scheinker syndrome (GSS). Here, we analyzed the properties of the pathological prion protein in six FFI cases by Wester...

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Principais autores: Wiebke Jürgens-Wemheuer, Arne Wrede, Walter Schulz-Schaeffer
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-10-01
Serier:Pathogens
Fag:
fatal familial insomnia
prion disease
prion types
stability
protein aggregates
deposition pattern
Online adgang:https://www.mdpi.com/2076-0817/10/10/1293
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