Altered adenosine 2A and dopamine D2 receptor availability in the 6-hydroxydopamine-treated rats with and without levodopa-induced dyskinesia

Several lines of evidence imply alterations in adenosine signaling in Parkinson's disease (PD). Here, we investigated cerebral changes in adenosine 2A receptor (A2AR) availability in 6-hydroxydopamine (6-OHDA)-lesioned rats with and without levodopa-induced dyskinesia (LID) using positron-emission t...

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Autori principali:	X. Zhou, J. Doorduin, P.H. Elsinga, R.A.J.O. Dierckx, E.F.J. de Vries, C. Casteels
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2017-08-01
Serie:	NeuroImage
Soggetti:	PET Parkinson's disease Dopamine D2 receptor Adenosine 2A receptor [11C]preladenant 6-OHDA-lesioned rats
Accesso online:	http://www.sciencedirect.com/science/article/pii/S105381191730469X
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