Methylation status of the SOCS 1 and JUNB genes in chronic myeloid leukemia patients Padrão de metilação dos genes SOCS 1 e JUNB em pacientes com leucemia mieloide crônica

Alterations in the methylation status of genes may contribute to the progression of Chronic Myeloid Leukemia (CML). In this study, the methylation status in exon2 of SOCS- 1 and promoter regions of both SOCS- 1 and JUNB were evaluated in CML patients. The methylation status of these genes was analyz...

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Hauptverfasser:	Márcia Cristina R. Pena, Maria Inês M. C. Pardini, Virgilio A. R. Colturato, Nídia A. Pinheiro
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2009-01-01
Schriftenreihe:	Revista Brasileira de Hematologia e Hemoterapia
Schlagworte:	Leucemia mieloide crônica metilação MSP- PCR SOCS- 1 JUNB Chronic myeloid leukemia methylation
Online-Zugang:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842009000300009
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