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The cellular protein MCM3AP is required for inhibition of cellular DNA synthesis by the IE86 protein of human cytomegalovirus.

Like all DNA viruses, human cytomegalovirus (HCMV) infection is known to result in profound effects on host cell cycle. Infection of fibroblasts with HCMV is known to induce an advance in cell cycle through the G(0)-G(1) phase and then a subsequent arrest of cell cycle in early S-phase, presumably r...

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Opis bibliograficzny
Główni autorzy: Emma Poole, Mark Bain, Linda Teague, Yoshinori Takei, Ron Laskey, John Sinclair
Format: Artigo
Język:Inglês
Wydane: Public Library of Science (PLoS) 2012-01-01
Seria:PLoS ONE
Dostęp online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0045686&type=printable
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