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Rapid Determination of 9 Tyrosine Kinase Inhibitors for the Treatment of Hepatocellular Carcinoma in Human Plasma by QuEChERS-UPLC-MS/MS

A reliable and rapid method employing QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) pretreatment coupled with ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) was successfully developed and validated for the analysis of nine tyrosine kinase inhibitors (TKIs)...

Täydet tiedot

Tallennettuna:
Päätekijät: Wen Jiang, Tingting Zhao, Xiaolan Zhen, Chengcheng Jin, Hui Li, Jing Ha
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2022-06-01
Sarja:Frontiers in Pharmacology
Aiheet:
tyrosine kinase inhibitors
UPLC-MS/MS
QuEChERS
plasma
hepatocellular carcinoma
Linkit:https://www.frontiersin.org/articles/10.3389/fphar.2022.920436/full
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